Brenda, when the drinking gets that bad there's not a whole lot that can be done until the drinker wants to quit and is 100% committed to getting sober. Only your mother can create the boundary for what she will tolerate, but it sure sounds like she's carrying far more than her share of the load. If your Mother is willing to retire early or dissolve the business if your sister continues to drink on her workdays, that is her right. Short of that, I don't see much changing unless you sister decides to get sober.