MK - I didn't really succeed on subs, but I did take them long enough to normalize. When the dosage was correct I would be feeling good by day 3. Induction was always terrible for me and the day after was very blah. By day 3 I would feel pretty good. I never stuck with it though, and would always stop taking it once I had a couple days of feeling good (once I had enough time to get my willpower up). Even when I was feeling good though the cravings never completely went away. They were significantly diminished though.