Neither of my sons can live here, after years of battling their addictions.
I wouldn't really care if they're sober for 10 years, they cannot move back in.
They can visit, and I lock everything up, but that's about all.
You may want to think about investing in a tumble combination lock.
AND your wife should be using a daily pill container that has a weeks worth of meds in it.
Prescription drugs are way to easy to abuse.
Sounds like you have your hands full.
Solution: Alanon mtgs. good support, good info.
hugs, and keep posting.