Spycekat,
If you are fasting or not eating properly, acetaminophen is VERY toxic, because the liver can't break it down.
From a medical site:
"In adults, the minimum toxic dose of APAP for a single ingestion is 7.5-10 g"
According to the same source, liver poisoning by acetaminophen has 4 clinical phases:
Phase 1 (0-24 h)
The first phase lasts up to 24 hours.
Patients have anorexia, nausea, vomiting, malaise, and diaphoresis (excessive sweating).
The second phase begins 24 hours after ingestion and lasts for another 48 hours. Phase 1 symptoms become less evident than before and/or resolve.
Patients present with pain and tenderness in the right upper quadrant. Liver enlargement (hepatomegaly) can be present. Some patients report having decreased urinary output.
Phase 3 develops 3-5 days after ingestion.
The symptoms seen in phase 1 (eg, anorexia, nausea, vomiting, malaise) may reappear. Patients have symptoms of hepatic failure with jaundice, hypoglycemia, bleeding, or encephalopathy. Renal failure and cardiomyopathy may also occur.
Hepatic centrilobular necrosis is evident on liver biopsy. Almost 4% of patients who develop this degree of hepatotoxicity progress to fulminant hepatic failure. Death may occur because of cerebral edema, sepsis, or multiorgan failure.
Phase 4 occurs 5-14 days after ingestion. This phase can last as long as 21 days. Patients either have a complete recovery of liver function or they die.
Whereas before your body may have been able to handle the meds, your losing weight may have changed your liver's ability to handle it.
Do you currently have a personal physician? Weight loss . . . malnutrition . . . feeling like you want to die . . . these things are NOT normal and are good reasons for medical evaluation without delay.
Please find a doctor and get some help.
Buzz