Genetics may or may not play a role in determining addiction. I think the issue is fairly complex.
Humans are thinking beings with free will. Hence, a genetic tendency to abuse a substance is far less important than the person's choices. A rat, a creature of instinct, is ruled by hard and fast rules of survival.
Addiction is likely the culmination of several factors, emotional, learned behaviour, and disposition. Although this THIQ is apparent in the alcoholic brain, it can't be the only reason for the progression of abuse.
So, although I may have increased the amount of THIQ in my brain, that by itself cannot be the reasons for my past relapses, or my addictive personality itself.
I doubt that there will ever be a magic pill or procedure to eliminate THIQ, and even if there were, this would not have much effect on a person's addictive tendencies.
Keep well
Ron