I'm very certain science does know quite a bit more about addiction from a biological standpoint now than was known back when AA was developed. The problem is, (IMHO) that human beings aren't strictly biological creatures. We also have psychological and spiritual components that are all interconnected, and what one does effects the others. Can addiction be arrested strictly thu manipulation of a biological mechanism? Perhaps. But addressing the underlying issues that cause addiction in some cases may go far deeper than mere biology. Like one of the other posters mentioned, arresting addiction will probably never be a one size fits all solution. Different people will respond to different methods.