Not even 48 hours. I drank Wednesday night into Thursday morning around 2am i'm guessing. I noticed the redness and bump on my nose in march and so i stopped drinking from March 12th to April 12th but i didn't notice any change within that month. If anything it got worse but with more of rosacea like symptoms rather then a red glow like it is now. For example my face would explode redness if i ate any hot foods or avocado. So I went to a dermatologist and got the creams and doxycyclin for the bump and learned all my triggers so i wouldn't get any rosacea flair ups anymore and the bump was going away so i started drinking again. Now for some reason I can eat hot foods and avocado with out anything happening to my face but now it's just red all day every day. It's very strange.