Not sure of the value of this, but the TIQ/ THIQ hypothesis is described as "discredited" by Dr. Wikipedia M.D. I looked up the papers in the references, but they are way beyond me I am afraid
I have read a lot of contradictory material on the physiological mechanism for alcoholism over the last three months, though the general model seems consistent. The genetic part of the puzzle is absolutely real. My AV has even had the thought of "Dude! Maybe they'll be a gene therapy sometime in the future so you can go back to drinking!"
