Absolutely. About a year ago I drank after a short period of abstinence and my hangover was much different than a non-alcoholic who drank ten beers.
I was slightly shaky (felt like my insides were trembling. Not shaking, but trembling). I was filled with anxiety. Not the mental type but the physical paranoid type. The worst was the crippling depression.
The hangover lasted about five days. The acute hangover feeling. Even a week later when I would do anything physical at work I would sweat profusely, like noticeably sweaty to people.
I've been sober nine months. If I were to drink tonight, say 8-10 beers (less than I used to drink. I used to drink 12-14 a night) I would be hungover for a week.
Kindling has a wonderful cure called abstinence.