yes. My incredible shrinking man was never large (5'10" 160 lb), but if he gets any smaller I will have to buy his pants in the kids' section. I wish that was joke, but he's become so thin I have trouble getting him pants in the men's section.
Looking at his belt you can see how he is changing from the wear and tear. He's also got sorta a humped back/neck/shoulders that you sometimes see in men much older.
He eats way less than I do, although he still walks the dog.
Before he was hospitalized he was constantly clearing his throat and had trouble swallowing too. They did all sorts of tests but I never heard of any determination around it, unless the doctors told him when I wasn't there. He left the hospital on a pablum type diet. His throat got better and he could eat normally after about a month.
It's scary to watch.