The medication label says to have had 12 hours without alcohol, most doctors recommend 24 hours so I would go for that. It is also a good idea to avoid foods cooked in alcohol (unless you are positive all the alcohol was cooked off), vinagers (like vinagerette salad dressings), and frostings (the alcohol in flavored-extracts can set you off, but it is cooked off in cookies, etc). I've read that a good way to tell if you are going to have a strong reaction is to swab your arm with alcohol 12 hours or so and see if you get a rash. If you do have a reaction then watch out for the face cleansers and moisturizers with alcohol. I know this sounds like a lot, but remember it is not permanent. Also, lots of people have no reactions to anything except actual booze. That being said, everyone has to avoid mouthwash and cold medicine with alcohol in it, obviously.