Untoxicated

You rang?

From what I understand "methylated" occurs as the addition of a methyl group to said molecule in an attempt to delay absorption of that molecule. I think, but don't quote me on this, that the methyl group is cleaved either in the liver or the small intestine and is then absorbed and exerts its effects as the active drug (it's a pro-drug/hormone prior to the cleaving).

In the case of bodybuilding it's a pro-hormone (the idea is a "legal" way to boost testosterone without using anabolic steroids). In the cases of stimulants, it's a pro-drug - such as the drug Vyvanse (the idea is to create a time-release of the drug and deter abuse).

That's my stab at it, I hope it helps.