While the depression may not fully lift, you stand a fighting chance at being able to get to the root of it and not make it any worse, I found alcohol to be "the best" anti-depressant of any drug whils't it was coarsing through my system on the intitial/main buzz but when coming out of blackout I found my mood to be incredibly hopeless and depreive to the extent where i felt taking another drink was the only/safest option, I literally couldn;t cope with such a low/hopeless mood.
Whils't i still struggle with some mild depressive/self-conscious issues they ain't half so bad as they got when i was binging.
The whole time I was on anti-depressives I was abusing booze and drugs very, very heavily, i used to refer to them as my rock as the come-downs off pills and coke seemed less anxiety based. I dunno man, drinking and drug taking will only take your overal mood/persona down into the gutter tbh. Horrible place to be and i don't want to go back there.