I take B12 too, most of the time. I take supplements of all the B vitamins and I really believe they help me to have energy and also to deal with stress. I take them in the AM and the PM. In fact, I think my body doesn't process B vitamins from food very well, and that's one of the things that had gotten me down physically and mentally, before I began drinking. And, then alcohol depletes the B vitamins in the body, so it got worse.