As for amends, I had one that I had to do. It was a woman that I behaved badly toward, and I owed it to her. Others I have not done, for various reasons.
As for disease, I feel alcoholism is mental, hereditary, and of course biological. The physical addiction is terrifying. Once that is dealt with, the mental issues have to be confronted. Relapse prevention is the goal. And if alcoholism runs in your family, I believe you are more likely to suffer from it. My two cents.