I've been on sertraline (zoloft) for at least 20 yrs now and it really makes a difference in my mood, keeps me level. When I was drinking, the antiD didn't work cause the alcohol was negating the effect of the drug.
I had to be sober for a while to notice the antiD working again. I wouldn't say it helped with my cravings, but I was much less inclined to drink as I had no depression or anxiety to numb out from.
I didn't start drinking because I was depressed, I started small, then became addicted. But once I was addicted, I drank to mask the alcohol-induced depression. It was a vicious cycle.
Now I'm sober over seven yrs and still take sertraline every day. My depression is much better, and by living sober, I am not creating despair.