Originally Posted by
Outonthetiles 
I need a list of excuses, and back up excuses to have at the ready:
"No thanks, alcohol interferes with my heart medication."
"No thanks, alcohol interferes with my Prozac."
"No thanks, alcohol interferes with my brain function."
The exercise excuse: drinking is not compatible with the kind and amount of exercise I do. My friends clearly understand this fact even without an explanation of the big picture. Most of my friends, if they knew the big picture reasoning, would start a big debate on the pros and cons of drinking which I would find upsetting and exhausting.