WOW,
What a very thought provoking thread. I have experienced the feeling you're talking about too, but probably to a far lesser degree. I have a feeling it's going to happen a number of times until it's effects are the same.
I described it as indifference too but it's a form of surrender, an "I give up." I think all of us in the back of our minds have some hope that the A in our lives will get sober and everyone will live happily ever after. Then I think sometimes, there's this defining moment, when you finally realize, not this A and not in this life.