Exercise!!! And lots of it. I manage my genetic chemical depression with yoga and have been able to stay off all meds. My sister tried every med in the book and ended up killing herself. Please understand I am not saying meds are bad in any way. In fact, I think they are appropriate in many cases. I just don't think they always work, and if someone is resistant to taking them, there are other things they can try first that might be as effective. The day I started yoga was the day I knew I had the chemical part of my problems under control. (It didn't cure the codependency though
).. Anyway, yoga was a miracle in my life. I don't know what would have happened to me without it. It isn't for everyone though, and men especially can have some resistance to it. Get your husband out for a long and strenuous walk in the sunshine and see if that helps him.