I was on regular Seroquel for nearly a year. I had to get off. Think I was only on 30 mg. No matter how early I took it, the grogginess would last for hours the next day. I'd have terrible nightmares and night sweats, and began sleepwalking/talking.
Just found out I am a narcoleptic... so this might just be me - but after a while, it was too much.
I hope you find something that works for you!