Here is one article:
Low Testo Opiates.
I have to take specially compounded testosterone cream for the next 6 weeks, and then have my blood levels re-tested. I'm a woman, and not to have a libido due to oxy's, as well as massive mood swings - I almost lost my best friend/boyfriend. Thankfully, he now knows and understands and we are working through this together.
And for you ladies in the 35-50 range: opiate abuse can throw you directly into perimenopause. Not fun. I'm 40, and am going through the whole gamut of menopausal effects. I wish I never picked up an oxy pill in my life. Now I have to pay the price.
Please learn from my experience.