Welcome to SR
My experience is that each time I went through a period of not drinking and would pick again my bodies reaction to alcohol had not improved. Toward the end of my drinking it did get worse with each unsuccessful attempt to quit drinking. My body reacted like I had not quit drinking at all. I was not being treated with anti-depressants during any of those times.
Unfortunately, I think it is true that the disease of alcoholism is always progressive never regressive. When we stop drinking although we may arrest the symptoms of alcoholism our bodies retain that memory of where we were at in our disease and when we pick back up we don't start at the beginning but where we left off.
That is just my experience though.