michael...
Sorry to know depression is part of your life.
Yes...the info above is interesting
but many strides have been made in treating depression
since those experiences/thoughts of Bill's were written.
I certainly hope you will find something that addresses your
particular type of depression......
I was diagnosed with situational depression from alcohol.
It seeon lifted with sobriety.I was very fortunate.
Many members of my AA home group take various medications
to deal with their mental conditions.
Blessings to you and your wife