for myself, the physical changes came apparent everytime I looked in the mirror....first the bloat and puffiness went away in my face and abdomen, I had incredible thirst and probably drank about a gallon of herbal tea every day the first week....i started sleeping better about 5-6 days and this made a difference too...i started to look well rested....after about 10 days, my BP and resting HR dropped down to more normal levels and i cut my HTN meds in 1/2...i stopped the PM dosing because my BP would get too low....took my B vitamins, multis, liver antioxidants and valarian to help me sleep.
after about 3 weeks i started some exercise every AM. it hleps with both my HTN and my mood is better throughout the day.