It's always best to be up front and honest with your DR and/or therapist. In some cases, they won't prescribe certain medications to you if they know about alcohol misuse/abuse. (Not sure about Zoloft) But yes--mixing booze and most medications (especially anti-depressants) aren't good. Also, if you think you might be drinking too much--chances are that you most likely are. Alcohol tolerance builds up over time....it just shows that your body has gotten used to having it in your system so it will take more and more alcohol to get the effect or "buzz" than what you drank before. It also isn't healthy. I would suggest that you be open/honest with your therapist. They aren't mind readers and if you are paying them to help you--then let them by first telling them the truth about what is going on.