Originally Posted by
zencat 
I could add that psychological dependence could very well be because of changes in brain chemistry and structure. Physical changes in the brain that is to say, hence tissue dependence maybe?
Maybe but I would say it is more likely learned ways of coping with my depression. Maladaptive ways, of course.
If what you have always (20+ years) done to cope with depression has been to drink then it becomes ingrained.
What you say might be true though.