| STREET TERM | DEFINITION |
| Backwards | Depressants |
| Bam | Amphetamine; depressants |
| Bambs | Depresants |
| Bank bandit pills | Depressants |
| Barb | Depressants |
| Barbies | Depressants |
| Beans | Crack Cocaine; mescaline; amphetamine; depressants |
| Black beauties | Amphetamine; depressants |
| Block busters | Depressants |
| Blue | Crack Cocaine; depressants; OxyContin |
| Blue angels | Depressants |
| Blue birds | Depressants |
| Blue bullets | Depressants |
| Blue clouds | Amytal (amobarbital sodium) capsules |
| Blue devil | Depressants |
| Blue dolls | Depressants |
| Blue heavens | Depressants |
| Blue tips | Depressants |
| Bombido | Heroin; injectable amphetamine; depressants |
| Bombita (Spanish) | Heroin plus amphetamine; depressants |
| Busters | Depressants |
| Candy | Cocaine; Crack Cocaine; amphetamine; depressants |
| Chorals | Depressants |
| Christmas rolls | Depressants |
| Christmas tree | Marijuana; amphetamine; methamphetamine; depressant |
| Coral | Depressant |
| Courage pills | Heroin; depressants |
| Disco biscuit | Depressants; methylenedioxymethamphetamine (MDMA) |
| Disco biscuits | Depressants; methylenedioxymethamphetamine (MDMA) |
| Dolls | Amphetamines; depressant; methylenedioxymethamphetamine (MDMA) |
| Double trouble | Depressants |
| Downer | Depressants |
| Downie | Depressants |
| Drowsy high | Depressants |
| G.B. | Depressants |
| Gangster pills | Depressants |
| Golf balls | Depressants |
| Goofball | Cocaine mixed with heroin; depressants |
| Goofers | Depressants |
| Gorilla pills | Depressants |
| Green dragons | Depressants |
| Green frog | Depressants |
| Idiot pills | Depressants |
| Inbetweens | Amphetamine; depressants |
| Jellies | Combination of depressants and MDMA (methylenedioxymethamphetamine) in gel form |
| Jelly bean | Amphetamine; depressants |
| Joy juice | Depressants |
| King Kong pills | Depressants |
| Lay back | Depressants |
| Lib (Librium) | Depressants |
| Little bomb | Heroin; amphetamine; depressants |
| Love drug | Depressants; methylenedioxymethamphetamine (MDMA) |
| Ludes | Depressants; methaqualone |
| Luding out | Depressants |
| Luds | Depressants |
| M&M | Depressants |
| Marshmallow reds | Depressants |
| Mexican reds | Depressants |
| Mickey Finn | Depressants |
| Mickey's | Depressant; LSD |
| Mighty Joe Young | Depressants |
| Mother's little helper | Depressants |
| Nebbies | Depressants |
| Nemmies | Depressants |
| Nimbies | Depressants |
| No worries | Depressant |
| On the nod | Under the influence of narcotics or depressant |
| Pancakes and syrup | Combination of glutethimide and codeine cough syrup |
| Peanut | Depressants |
| Peter | Depressants |
| Peth | Depressant |
| Phennies | Depressants |
| Phenos | Depressants |
| Pink ladies | Depressants |
| Purple hearts | LSD; amphetamine; depressants |
| Q | Depressants |
| Quads | Depressants |
| Quas | Depressants |
| Rainbows | Depressants |
| Red and blue | Depressants |
| Red bullets | Depressants |
| Red devil | Depressants; PCP; heroin |
| Red rock opium | Heroin, barbital, strychnine, and caffeine |
| Red rum | Heroin, barbital, strychnine, and caffeine |
| Red stuff | Heroin, barbital, strychnine, and caffeine |
| Reds | Depressants |
| Schoolboy | Cocaine; codeine |
| Seccy | Depressants |
| Seggy | Depressants |
| Sleeper | Heroin; depressants |
| Sleeper and red devil | Herion plus a depressant |
| Softballs | Depressants |
| Sopers | Depressants |
| Speedballing | To shoot up or smoke a mixture of cocaine and heroin; ecstasy mixed with ketamine; the simultaneous use of a stimulant with a depressant |
| Stoppers | Depressants |
| Strawberries | Depressants |
| Stumbler | Depressants |
| Tooles | Depressants |
| Tooties | Depressants |
| Tranq | Depressants |
| Tuie | Depressants |
| Uncle Milty | Depressants |
| Ups and downs | Depressants |
| V | The depressant Valium |
| Yellow | LSD; depressants |
| Yellow bullets | Depressants |
| Yellow jackets | Depressants; methamphetamine |
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