Not exactly sure what's wrong...

[Vintersemestre]

I'm positive I'm depressed, with anxiety (they like to go hand-in-hand). However, after I stopped using (opiates) this sort of "brain fog" started to develop, almost like disassociation or derealization but not quite as severe. I just feel like everything I do is useless and everything I say is without the barest of meaning or consequence. I'm hoping this is just my mind's safe-mode reaction to the depression and anxiety and not some other disorder (like I need more of them).

Meds I'm currently taking:

Effexor 75mg in the morning, then 37.5mg in the afternoon.
Klonopin up to 1.5mg as needed.
Seroquel XR 50mg in the evening.

I feel that they do help... they get me out of bed at least and I tend to worry less, but I obviously still do.

Any veteran input would be appreciated...

[nandm]

How long have you been off the opiates? It can take some time for the fog from withdrawls to clear. That may be part of the problem. I personally do not have any experience with opiates as my problem was alcohol. But from what I have read they do affect the brain chemistry and dopamine receptors and that effect can be long term. Seroquel also can leave some people feeling disassociated or zombie like. It also works really well for some people. I would suggest talking to your doctor to see what other medication options are available and if this could be a result of the removal of the drugs. Let us know what you learn as I am sure there are others out there with similiar experiences.

[endzoner]

I have no experience in this area V . But i do have experience in giving a friend a

[Vintersemestre]

I've been off them since August 23rd, but I've had depression before using too.

[liveweyerd]

i have been prescribed all of those drugs.

The combination of klonopin and seroquel concerns me a bit.

Mostly the seroquel.

Many Drs are now using seroquel for anxiety but that is NOT what it was developed for or is FDA approved for.

My husband and I both had terrible reactions to it and I have heard many people report similar problems.

klonopin is commonly used for anxiety and is usually effective, perhaps talk to your Dr about your dosage.
Your Effexor dosage may need to be adjusted as well, or another antidepressant added.

I cannot give medical advice, this is solely my experience.

It took quite a while to tweek my meds so that they worked properly.

[reader]

I take 150mg of the Effexor twice a day and the 50 mg of the Seroquel with good results.. You just may need to have ur ad adjusted. I hope u feel better soon...

[unholy_mess]

I've been taking Seroquel for a few weeks...I take it basically for insomnia, but find that if I try to stay awake instead of falling asleep as soon as it hits me, I become very dissociated and sort of "space out" and find that time passes without my being aware...and I'm only on 25mg....I cut back from 50mg because when I woke up in the mornings, I was really foggy and sort of out of it. It cleared eventually though...I doubt that's the sole contributor, but could be playing a part...