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I was recently put on Lexapro for major depression. It worked about as well as asprin. My depression got dangerously worse. Then, my Doc added Wellbutrin with it. She said they work better together, esp with anxiety. Oh My God! My world changed in 1.5-2wks total. You're already on Wellbutrin, which is supposed to give you "energy" anyway. Maybe the Lexapro fatigue wont bother you this time. I just know that the combination was a life saver for me. Good Luck. Its hard work being a sufferer of Major Depression/bipolar. I do understand.
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