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certain antacid medicines like tagamet and the such can be used to potentiate opiate absorbtion in the body by blocking certain liver enzymes. I'm not sure if prilosec falls into that catagory, also grapefruit juce does the same thing so be suspicious if he suddenly starts drinking it and eating tagamet.
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Warning: I'm a sick person so take any advice I may be spewing with a grain of salt, but it's what has worked for me, so far.
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