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OmEgA-X1 · 04-15-2005, 03:07 PM

As you know cocaine is not a hallucinogen, the method of its action produces little effect but to release dopamine which causes addiction. Hallucinogens do not have much effects on the dopamine system (short of ecstasy and maybe a few other rare cases I do not know of) and are not addicting. In fact, hallucinogenic chemicals have been found to be the most successful treatment for addictions, especially serious ones like that for Heroin. Almost all hallucinogens have effects on the serotonin system.

Salvinorin A is a very special case however, and is truely unique. Till 2002 the method of action was unknown. Recently however it has been found to be the only natural hallucinogen to work on the kappa-opioid receptors. There have been synthetic drugs that are kappa-opioid receptor agonists created in the past, namely Enadoline, which has reportedly similar effects of Salvinorin A (possibly even identical).

Very little is actually known about the kappa-opioid receptors except for its unusual psychedelic effects. Research is vauge and suggests it is part of a system to modulate human perception.

However, as far as psychosis and delusions go, I suspect the actions of this hallucinogen to be very similar to those acting on the serotonin system, meaning they do not actually induce or cause those effects, but merely bring those latent functions forward. Like I've stated, Salvinorin A has been consumed for milenia with no reported cases of it causing any form psychosis or schizophrenia, and I'm very interested in learning the outcome of your son, Mamabear.

If your son does not seem to get better Mamabear, would I be so bold as to say you should suggest to your doctor or psychiatrist the use of naltrexone (general opioid antagonist)? Technically it should block the effects of Salvinorin A, and possibly any psychosis or delusions related to the kappa-opioid system. Then again, your son may very well become completely normal once the Salvinorin A completely leaves his system, which is a total of three days. It is said though the general effects of Salvinorin A only last a total of 30 minutes, there are very mild usually unnoticable effects lasting until the 3 day mark. This is a most interesting learning experience...

04-15-2005, 03:07 PM	#4 (permalink)
OmEgA-X1 Member Join Date: Apr 2005 Location: Indianapolis, IN Posts: 2	As you know cocaine is not a hallucinogen, the method of its action produces little effect but to release dopamine which causes addiction. Hallucinogens do not have much effects on the dopamine system (short of ecstasy and maybe a few other rare cases I do not know of) and are not addicting. In fact, hallucinogenic chemicals have been found to be the most successful treatment for addictions, especially serious ones like that for Heroin. Almost all hallucinogens have effects on the serotonin system. Salvinorin A is a very special case however, and is truely unique. Till 2002 the method of action was unknown. Recently however it has been found to be the only natural hallucinogen to work on the kappa-opioid receptors. There have been synthetic drugs that are kappa-opioid receptor agonists created in the past, namely Enadoline, which has reportedly similar effects of Salvinorin A (possibly even identical). Very little is actually known about the kappa-opioid receptors except for its unusual psychedelic effects. Research is vauge and suggests it is part of a system to modulate human perception. However, as far as psychosis and delusions go, I suspect the actions of this hallucinogen to be very similar to those acting on the serotonin system, meaning they do not actually induce or cause those effects, but merely bring those latent functions forward. Like I've stated, Salvinorin A has been consumed for milenia with no reported cases of it causing any form psychosis or schizophrenia, and I'm very interested in learning the outcome of your son, Mamabear. If your son does not seem to get better Mamabear, would I be so bold as to say you should suggest to your doctor or psychiatrist the use of naltrexone (general opioid antagonist)? Technically it should block the effects of Salvinorin A, and possibly any psychosis or delusions related to the kappa-opioid system. Then again, your son may very well become completely normal once the Salvinorin A completely leaves his system, which is a total of three days. It is said though the general effects of Salvinorin A only last a total of 30 minutes, there are very mild usually unnoticable effects lasting until the 3 day mark. This is a most interesting learning experience...