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If you are mainly depressive, the Wellbutrin works differently then the Lexapro in that
it doesn't affect the Serotonin like the SSRI's. which seem to work better for just depression. Have you tried Celexa? Lexapro is just an updated version, Also maybe a combination. I have been on all the above at one time or another, and a combination
worked the best for my situation at the time. It would be impossible to recommend any particular drug, or combination, that is up to you and your Pdoc. The hardest thing to deal with, at least for me was all the trial and error I had to go through to find something that could help. BTW in my case it would not even be debatable, my depression took me into a pit of hopelessness, I don't know if I could even describe it accurately, nothing would ever be worth existing in that much mental pain again, for any reason. Don't quit looking.
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