[nandm]

My experience with anti-depressants has been that although they have worked well for me, up until the latest one they have always seemed to stop working at some point. I was able to be on Prozac for nearly 2 years before it stopped working, paxil 6 months, lexapro a little over a year and a half, and currently Cymbalta has been working for nearly 2 years now although I did have to have the dose increased.

I am also bi-polar type II which typically presents with a hard to treat depression anyway so my experience if probably not typical.