There is also one drug that is not in any family called Desyrel(Trazodone)
Quote:
|
Originally Posted by NIH Trazodone is used to treat depression. Trazodone is in a class of medications called serotonin modulators. It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance. |
http://www.nlm.nih.gov/medlineplus/d...r/a681038.html
Have you ever tried the tricyclic antidepressants? These are the ones that were around before SSRIs. For years, I was on one of them, Tofranil (Imipramine). This was before the SSRI's and it worked wonders for 6 years for me. If I ever get that depressed again I will ask to be put back on that one, over the SSRIs (I'm on paxil for my anxiety now).
Tofranil worked so well that through the 80s it was the drug that they used in clinical trials to determine whether another drug was worth pursusing financially. If it didn't work as well as Tofranil studies were stopped.
Also in this family is Sinequan (doxepin) and Elavil.